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Pooled sensitivity and specificity of ASCA-IgG and IgG/IgA for diagnosis of GIBD assessed by ELISA and IIF
| Methods | ELISA | IIF | ||
| Diagnostic accuracy | Pooled sensitivity (95% CI) | Pooled specificity (95% CI) | Sensitivity | Specificity |
| ASCA-IgG | 0.20 (0.12 to 0.31) | 0.93 (0.86 to 0.98) | 0.44 | 0.91 |
| ASCA-IgG/IgA | 0.33 (0.23 to 0.44) | 0.85 (0.76 to 0.91) | 0.15 | 0.96 |
ASCA, anti-Saccharomyces cerevisiae antibodies; GIBD, gastrointestinal Behçet’s disease; IIF, indirect immunofluorescence assay.
