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. 2020 Oct 6;8(1):e001537. doi: 10.1136/bmjdrc-2020-001537

Figure 1.

Figure 1

Participant study flow diagram for metformin group. *Permanently discontinued from metformin during the DPP either because fasting plasma glucose ≥140 mg/dL or other protocol deviations and thus ineligible to take study metformin. †This includes 216 participants diagnosed with diabetes during the DPP, but with fasting plasma glucose <140 mg/dL. ‡For those eligible to take study metformin at DPPOS baseline (n=868), 216 (24.9%) were diagnosed with diabetes during DPP and a further 235 (27.1%) were diagnosed during DPPOS follow-up. In those who never took any study metformin during DPPOS (n=204), 59 (28.9%) were diagnosed during DPP while a further 48 (23.5%) were diagnosed during DPPOS. In those who took study metformin at one or more DPPOS visits (n=664), 157 (23.6%) were diagnosed during DPP while a further 187 (28.2%) were diagnosed during DPPOS. DPP, Diabetes Prevention Program; DPPOS, DPP Outcomes Study.