TABLE 4.
Pathological scores between patients with plasma BKPyV-DNA load ≥ the threshold and those with plasma BKPyV-DNA load < the threshold.
| Parameters | BKPyV-DNA load ≥ 103 copies/mL (n = 57) | BKPyV-DNA load < 103 copies/mL (n = 19) | P | BKPyV-DNA load ≥ 104 copies/mL (n = 36) | BKPyV-DNA load < 104 copies/mL (n = 40) | P | BKPyV-DNA load ≥ 105 copies/mL (n = 19) | BKPyV-DNA load < 105 copies/mL (n = 57) | P |
| Extent of SV40-T staining (%) | 15.8 ± 9.2 | 15.0 ± 13.7 | 0.781 | 16.7 ± 8.9 | 14.6 ± 11.6 | 0.366 | 20.1 ± 8.9 | 14.1 ± 10.5 | 0.027 |
| Pathological Banff scores | |||||||||
| t | 1.7 ± 0.7 | 1.3 ± 0.7 | 0.070 | 1.7 ± 0.6 | 1.5 ± 0.8 | 0.099 | 1.9 ± 0.7 | 1.5 ± 0.7 | 0.055 |
| i | 0.8 ± 0.9 | 0.7 ± 0.9 | 0.681 | 0.9 ± 0.9 | 0.7 ± 0.9 | 0.254 | 1.4 ± 0.9 | 0.6 ± 0.8 | 0.004 |
| ct | 1.8 ± 0.8 | 1.7 ± 0.7 | 0.819 | 1.7 ± 0.7 | 1.9 ± 0.8 | 0.313 | 1.9 ± 0.6 | 1.7 ± 0.8 | 0.476 |
| ci | 1.8 ± 0.8 | 1.7 ± 0.6 | 0.605 | 1.8 ± 0.7 | 1.9 ± 0.7 | 0.613 | 1.9 ± 0.6 | 1.8 ± 0.7 | 0.642 |
| BKPyVAN stage (%) | 0.649 | 0.366 | 0.649 | ||||||
| A | 4 (7.0) | 1 (5.3) | 3 (8.3) | 2 (5.0) | 1 (5.3) | 4 (7.0) | |||
| B | 46 (80.7) | 17 (89.4) | 31 (86.1) | 32 (80.0) | 17 (89.4) | 46 (80.7) | |||
| C | 7 (12.3) | 1 (5.3) | 2 (5.6) | 6 (15.0) | 1 (5.3) | 7 (12.3) |
BKPyV, BK polyomavirus; t, tubulitis; i, interstitial inflammation; ct, tubular atrophy; ci, interstitial fibrosis; BKPyVAN, BK polyomavirus associated-nephropathy.