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. 2020 Sep 23;11:573823. doi: 10.3389/fimmu.2020.573823

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Copyright © 2020 Wei, Wang, Kuang, Wu, Zhao, Zhang, Li, Zheng, Zhang, Long, Guo, Nie, Yang and Tong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemistry of CD3 and ICAM1 in mouse tumor tissue. (A) Representative images of ICAM1 IHC staining in tumor sections after treatment. Scale bars = 50 μm. (B) Detection of CD3 on tumor tissue from the MDA-MB-231 and SKBR3 xenograft mouse models. (C) ICAM1 staining intensities in all treatment groups from the MDA-MB-231 and SKBR3 xenograft mouse models. (D) Determination of the number of CD3-positive cells by cell counting. Each datum represents three independent experiments (bar value represents the dispersion degree, ***p < 0.001).