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Predicted mean difference estimates and average 95% predicted intervals based on the observed mean difference of (0.2, 0.2) or (0.0, 0.0), the standard deviation of 1.0 and the correlation between the endpoints of 0.5, assuming the current trend continues or the null/alternative hypothesis is true, when 258 participants are observed (the planned sample size is 516). The number of generated datasets is 100,000.
