Appendix 1.

Agency for Health Care Policy and Research unstable angina guideline risk groups.

Risk of Complications	Criteria
High	At least 1 of the following features must be present:
	Prolonged ongoing (>20 minutes) rest pain
	Pulmonary edema, most likely related to ischemia
	Angina at rest with dynamic ST changes ≥1 mm
	Angina with new or worsening mitral regurgitation murmur, S3, new or worsening rales, or hypotension
Intermediate	No high-risk feature but must have any of the following:
	Prolonged ongoing (>20 minutes) rest angina, now resolved, with moderate-to-high likelihood of coronary artery disease
	Rest angina (>20 minutes or relieved with rest or sublingual nitroglycerin)
	Nocturnal angina
	Angina with dynamic T-wave changes
	New-onset Canadian Cardiovascular Society Classification grade III or IV angina in the past 2 weeks
	Pathologic Q waves or resting ST depression ≤1 mm in multiple-lead groups (anterior, inferior, lateral)
	Age >65 years
Low	No high- or intermediate-risk features but may have any of the following features:
	Increased angina frequency, severity, or duration
	Angina provoked at a lower threshold
	New-onset angina with onset 2 weeks to 2 months before presentation
	Normal or unchanged ECG