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. 2020 Sep 1;10(9):2785–2799.

Figure 7.

Figure 7

Depletion of TAZ in lung cancer inhibits cell proliferation and migration. A. Knockdown of TAZ by shTAZ-1 and shTAZ-2 in the NSCLC cell line A549. The effect of shTAZs on the protein level of TAZ and the target gene product CYR61 was determined by immunoblotting of the cell lysates with anti-TAZ and anti-CYR61 antibodies. B. The knockdown of TAZ by shTAZs inhibits A549 cell proliferation. The data used for quantitation were from three independent experiments. C and D. Knockdown of TAZ by shTAZs inhibits A549 cell migration. C. The wound-healing cell migration assay; D. The transwell cell migration assay. EGF (50 ng/ml) was used for stimulation of cell migration. The data quantification was the same as described in Figure 2. **P < 0.01; ***P < 0.001.