Table 1.
Patient characteristics
| Healthy (n = 15) | Late‐onset preeclampsia (n = 8) | Early‐onset preeclampsia (n = 6) | |
|---|---|---|---|
| Maternal age (y) | 28 (24‐30) | 29 (26.25‐28.75) | 26.0 ± (25.0‐2875) |
| Ethnicity (%) | |||
| White | 86.67 | 75 | 100 |
| Assyrian | 13.33 | 25 | 0 |
| Gestational age (wks) | 39.29 (39.0‐39.86) | 38.14 (37.14‐38.79) a (P = .04) | 30.65 (29.29‐31.32) a (P < .0001) b (P < .0001) |
| Parity | 1 (1‐2) | 1 (1‐2) | 1 (1‐3) |
| Body mass index (kg/m2) | 24.30 (20.35‐26.07) | 26.25 (21.65‐34.96) | 23.85 (21.03‐26.85) |
| Gestational age at onset of preeclampsia (wks) | 37.21 (35.97‐38.21) | 30.0 (28.4‐30.71) b (P < .0001) | |
| Diastolic blood pressure (mmHg) | 80.0 (72.0‐81.0) | 94.0 (86.75‐99.63) a (P = .0038) | 98.50 (89.0‐102.5) a (P = .0009) |
| Systolic blood pressure (mmHg) | 120.0 (110.0‐122.1) | 138.8 (131.3‐155.0) a (P = .0079) | 152.5 (140.0‐172.8) a (P = .0002) |
| Duration of hypertension (days) | 4.5 (1.0‐14.0) | 4.5 (3.0‐7.5) | |
| Random urine protein:creatinine ratio | 0.80 (0.60‐0.93) | 9.35 (1.84‐17.85) b (P = .007) | |
| Corticosteroid therapy for fetal lung maturation (% of patients) | 0 | 0 | 100 a (P < .0001) b (P < .0001) |
| Number of days between last dose of corticosteroids and childbirth (days) | 2.5 (2.0‐5.25) | ||
| Mode of delivery (%) | |||
| Vaginal | 66.67 | 75.0 | 0 a (P = .011) b (P = .021) |
| Spontaneous | 93.33 | 37.50 | 0 |
| Induction on maternal indication | 0 | 62.50 | 0 |
| Induction on fetal indication | 6.67 | 0 | 0 |
| CS | 33.33 | 25.0 | 100 a (P = .011) b (P = .021) |
| Breech presentation | 33.33 | 0 | 0 |
| Previous CS | 66.67 | 50.0 | 0 |
| Fetal indication | 0 | 50.0 | 16.67 |
| Maternal indication | 0 | 0 | 83.33 |
| Birth weight (g) | 3410 (3080‐3680) | 3115 (2698‐3361) | 1235 (990‐1459) a (P < .0001) b (P < .0001) |
| % Below 10th percentile birthweight | 0 | 25 | 66.67 a (P = .0008) |
| Fetal sex (% female/male) | 40/60 | 12.5/87.5 | 66.7/33.3 |
| Time between delivery and start of placental processing (hours) | 6.50 (0‐17.50) | 10.5 (1.38‐17.75) | 17.50 (0.38‐19.25) |
| Amount of cells isolated per mL decidual tissue (106) | |||
| Decidua parietalis | 0.17 (0.063‐0.21) | 0.62 (0.34‐0.90) | 0.11 (0.052‐0.39) |
| Decidua basalis | 0.20 (0.076‐0.45) | 0.63 (0.23‐1.0) | 0.12 (0.10‐0.24) |
Data as median with interquartile range; CS, cesarean section; blood pressure, highest blood pressure measured; duration of hypertension, time from first notice of hypertension until birth; statistical analysis by Kolmogorov‐Smirnov test, one‐way ANOVA and Tukey's post hoc test, Kruskal‐Wallis and Dunnett's test, or Fisher's exact test.
a
Shows comparisons to healthy pregnancies.
b
Shows comparisons to late‐onset preeclampsia.