TABLE 4.
OR of being a CH case at the extremes of the blood iodine distribution1
| Extreme iodine values2 | OR (95% CI) | Adjusted OR (95% CI)3 |
|---|---|---|
| Lowest 6.8% (0–0.0354 ng/mL, n = 124) | 1.16 (0.81, 1.68) | 1.38 (0.89, 2.16) |
| Lowest 10% (0–4.10 ng/mL, n = 182) | 1.09 (0.80, 1.48) | 1.24 (0.86, 1.81) |
| Lowest 25% (0–12.3 ng/mL, n = 455) | 1.08 (0.87, 1.34) | 1.10 (0.85, 1.42) |
| Highest 25% (30.3–820 ng/mL, n = 452) | 0.92 (0.74, 1.14) | 1.04 (0.81, 1.34) |
| Highest 10% (47.1–820 ng/mL, n = 181) | 0.84 (0.62, 1.14) | 0.94 (0.65, 1.36) |
| Highest 5% (66.0–820 ng/mL, n = 91) | 0.75 (0.49, 1.14) | 0.82 (0.49, 1.34) |
| Highest 3% (80.4–820 ng/mL, n = 55) | 0.67 (0.38, 1.14) | 0.82 (0.43, 1.56) |
1
CH, congenital hypothyroidism; NICU, neonatal intensive care unit.
2
Percentiles <6.8 could not be calculated due to the presence of samples below the limit of detection.
3
Adjusted for race/ethnicity (Asian, Black, Hispanic, Non-Hispanic white, other), sex (male, female), nursery type (regular nursery, NICU, other), birthweight (<1500 g, 1500–2499 g, 2500–3000 g, >3000 g), gestational age, age at screening, and mother's age. Infants with unavailable data for sex or nursery were excluded from analysis.