Figure 5.

Hypoxia pretreatment can improve the recovery efficiency elicited by USCs in a chronic liver fibrosis mouse model. A. Evaluation of liver index and the serum level of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Exogenous cells were visualized using fluorescent imaging. B. Representative H&E and Masson staining images. C. Representative images of immunohistochemistry for α-SMA, MPO, and 8-OHdG. D. Statistical quantification of Masson staining and immunohistochemistry. *P<0.05, **P<0.01, ***P<0.001, one-way ANOVA. Scale bar =200 μm. (α-SMA - α-smooth muscle actin, MPO - myeloperoxidase, 8-OHdG - 8-hydroxy-2’-deoxyguanosine).