Table 3.

Correlation of candidate genes with CSF biomarkers in AD patients

Samples	Items	Lnc-MALAT1		MiR-125b		FOXQ1		PTGS2		CDK5
		P value	r	P value	r	P value	r	P value	r	P value	r
CSF (N = 50)	Aβ42	0.107	0.230	0.209	-0.181	0.362	0.132	0.049	-0.280	0.041	-0.289
	t-tau	0.001	-0.466	0.003	0.408	0.053	-0.275	0.034	0.300	0.083	0.248
	p-tau	< 0.001	-0.494	0.003	0.418	0.002	-0.419	0.019	0.331	0.041	0.290
Plasma (N = 120)	Aβ42	0.008	0.241	0.110	-0.147	0.162	0.129	0.003	-0.271	0.023	-0.207
	t-tau	0.256	-0.103	0.073	0.164	0.450	-0.070	0.110	0.146	0.102	0.150
	p-tau	0.053	-0.177	0.039	0.189	0.373	-0.080	0.034	0.194	0.111	0.146

Correlation was determined by Spearman’s rank correlation test. CSF, cerebrospinal fluid; AD, Alzheimer’s disease; Lnc-MALAT1, long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1; miR-125b, microRNA 125b; FOXQ1, forkhead box Q1; PTGS2, prostaglandin-endoperoxide synthase 2; CDK5, cyclin dependent kinase 5; Aβ42, amyloid β 42; t-tau, total tau; p-tau, phosphorylated tau.