Figure 6.

OM inhibited tumor growth in vivo. A-C. In nude mice, tumor growth (tumor volume, tumor weight and the tumor size) was inhibited by OM in vivo and has a concentration dependent effect. D. Immunohistochemical assay revealed that the relative number of Ki67 positive expression cells in OM-treated group were considerably lower versus the control group in certain dose-dependent pattern. E. miR-367-3p expression in tumors of OM-treated group was considerably higher versus control group. F, G. The SGK3 expression in tumor of OM-treated group was notably lower relative to control group. (*P < 0.05).