Table 3.

Correlation analysis between STAT5A and gene biomarkers of immune cells in STAD (TIMER)

Immune cells	Biomarkers	None		Purity
		Cor	P-value	Cor	P-value
CD8+ T cell	CD8A	0.514	***	0.479	***
	CD8B	0.292	***	0.259	***
T cell (general)	CD3D	0.461	***	0.424	***
	CD3E	0.489	***	0.454	***
	CD2	0.488	***	0.455	***
B cell	CD19	0.385	***	0.356	***
	CD79A	0.392	***	0.362	***
Monocyte	CD86	0.437	***	0.416	***
	CD115 (CSF1R)	0.496	***	0.488	***
TAM	CCL2	0.258	***	0.228	***
	CD68	0.313	***	0.296	***
	IL10	0.436	***	0.411	***
M1 Macrophage	INOS (NOS2)	0.103	*	0.104	*
	IRF5	0.295	***	0.257	***
	COX2 (PTGS2)	0.06	0.224	0.044	0.392
M2 Macrophage	CD163	0.465	***	0.452	***
	VSIG4	0.386	***	0.376	***
	MS4A4A	0.476	***	0.452	***
Neutrophils	CD66b (CEACAM8)	-0.019	0.693	-0.041	0.429
	CD11b (ITGAM)	0.565	***	0.548	***
	CCR7	0.452	***	0.42	***
Natural killer cell	KIR2DL1	0.18	***	0.147	**
	KIR2DL3	0.165	***	0.129	*
	KIR2DL4	0.233	***	0.186	***
	KIR3DL1	0.22	***	0.202	**
	KIR3DL2	0.317	***	0.285	***
	KIR3DL3	0.074	0.133	0.064	0.214
	KIR2DS4	0.133	**	0.094	0.0674
Dendritic cell	HLA-DPB1	0.477	***	0.454	***
	HLA-DQB1	0.395	***	0.349	***
	HLA-DRA	0.48	***	0.45	***
	HLA-DPA1	0.49	***	0.463	***
	BDCA-1 (CD1C)	0.392	***	0.356	***
	BDCA-4 (NRP1)	0.342	***	0.306	***
	CD11c (ITGAX)	0.487	***	0.466	***
Th1	T-bet (TBX21)	0.525	***	0.497	***
	STAT4	0.467	***	0.452	***
	STAT1	0.241	***	0.226	***
	IFN-γ (IFNG)	0.291	***	0.267	***
	TNF-α (TNF)	0.206	***	0.165	**
Th2	GATA3	0.357	***	0.321	***
	STAT6	0.235	***	0.251	***
	STAT5A	-	-	-	-
	IL13	0.131	**	0.138	***
Tfh	BCL6	0.263	***	0.235	***
	IL21	0.312	***	0.27	***
Th17	STAT3	0.45	***	0.43	***
	IL17A	-0.098	0.0469	-0.106	0.04
Treg	FOXP3	0.45	***	0.419	***
	CCR8	0.505	***	0.481	***
	STAT5B	0.516	***	0.533	***
	TGFb (TGFB1)	0.367	***	0.357	***
T cell exhaustion	PD-1 (PDCD1)	0.482	***	0.448	***
	CTLA4	0.351	***	0.308	***
	LAG3	0.393	***	0.364	***
	TIM-3 (HAVCR2)	0.49	***	0.467	***
	GZMB	0.269	***	0.227	***

*P < 0.05, **P < 0.01, ***P < 0.001.