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Downregulation of CD44 expression does not affect chemoresistance under irinotecan (CPT-11) treatment in colon cancer cell lines. A. Downregulation of CD44 expression does not affect cell growth under CPT-11 treatment (20 μM) in SW480 cells (with CD44s protein). B. Downregulation of CD44 expression does not affect cell growth under CPT-11 treatment (20 μM) in HT29 cells (with CD44v protein). β-actin is used as an internal control.
