Table 2.
Comparison of clinico-pathological factors between negative and positive CD44 expression in patients with conversion hepatectomy (n = 52)
| Variable | CD44- (n = 33) | CD44+ (n = 19) | P-value |
|---|---|---|---|
| Age | 67 (45-82) | 61 (35-83) | 0.203 |
| Sex (male/female) | 20/13 | 11/8 | 0.848 |
| Synchronous/Metachronous | 23/10 | 11/8 | 0.389 |
| Molecular targets (present/absent) | 13/20 | 13/6 | 0.044 |
| Tumor size prior to hepatectomy (mm) | 24 (5-160) | 35 (11-60) | 0.549 |
| Tumor number prior to hepatectomy | 2 (1-13) | 3 (1-19) | 0.250 |
| CEA prior to hepatectomy (ng/mL) | 6.3 (1.3-173) | 6.2 (1-161) | 0.768 |
| RECIST PR/SD or PD | 22/11 | 10/9 | 0.316 |
| Ki-67 in the residual cancer cells (negative/positive) | 17/16 | 2/17 | 0.003 |
CEA, carcinoembryonic antigen; PR, partial response; SD, stable disease; PD, progressive disease.