Table 3.
Prognostic analyses of clinico-pathological parameters in patients with conversion hepatectomy for initially unresectable colorectal liver metastases (n = 52)
| Parameter | HR | Exp (B) | P-value |
|---|---|---|---|
| Disease-free survival | |||
| Tumor size prior to hepatectomy > 3 cm | 1.882 | 0.975-3.632 | 0.060 |
| Tumor number prior to hepatectomy ≥ 3 | 1.525 | 0.789-2.945 | 0.209 |
| CEA prior to hepatectomy > 7 ng/mL | 2.795 | 1.388-5.631 | 0.004 |
| RECIST SD or PD | 1.674 | 0.849-3.302 | 0.137 |
| CD44-positive in the residual cancer cells | 2.570 | 1.293-5.111 | 0.007 |
| Overall survival | |||
| Tumor size prior to hepatectomy > 3 cm | 1.825 | 0.656-5.081 | 0.249 |
| Tumor number prior to hepatectomy ≥ 3 | 1.471 | 0.546-3.964 | 0.446 |
| CEA prior to hepatectomy > 7 ng/mL | 2.521 | 0.874-7.275 | 0.087 |
| RECIST SD or PD | 4.355 | 1.569-12.087 | 0.005 |
| CD44-positive in the residual cancer cells | 3.457 | 1.159-10.316 | 0.026 |
Cox regression analyses were used. CEA, carcinoembryonic antigen; SD, stable disease; PD, progressive disease.