Table 1.
Effect of different dosage of IONPs on hematological indices (WBC, RBC, HGB, HCT, MCV, MCH, MCHC and PLT) in Wistar rat at day 28
| Tests | Control | Vehicle control | Low dose | Medium dose | High dose |
|---|---|---|---|---|---|
| WBC (*103/μL) | 8.4 ± 1.1 | 9.2 ± 4.3 | 6.7 ± 1.9 | 8.2 ± 1.5 | 12 ± 6.7 |
| RBC (*106/μL) | 7.7 ± 0.3 | 7.6 ± 0.3 | 7.2 ± 0.8 | 8.2 ± 1.2 | 8.1 ± 1.9 |
| HGB (g/dL) | 16.2 ± 1.5 | 13.5 ± 0.7 | 13.3 ± 1.8 | 14.5 ± 2.3 | 13.8 ± 1.5 |
| HCT (%) | 46.7 ± 1.8 | 50.5 ± 2.6 | 49.9 ± 6.1 | 56.2 ± 8.0 | 47.2 ± 5.4 |
| MCV (fL) | 60.3 ± 2.7 | 66.8 ± 0.8 | 69.2 ± 1.8 | 68.2 ± 0.2 | 62.7 ± 0.6 |
| MCH (pg) | 18.4 ± 0.3 | 17.8 ± 0.2 | 18.4 ± 0.8 | 17.6 ± 0.4 | 18.6 ± 0.5 |
| MCHC (g/dL) | 31.8 ± 1.6 | 26.7 ± 0.1 | 26.7 ± 0.6 | 28.1 ± 0.6 | 29.2 ± 0.4 |
| PLT (*103/μL) | 871 ± 5.4 | 789 ± 4.6 | 939 ± 2.3 | 777 ± 5.2 | 638 ± 3.1 |