Table 1.
In situ technique | Abbreviation | Description |
---|---|---|
Abdominal‐normothermic regional perfusion | A‐NRP |
Oxygenated blood pumped by an extracorporeal circuit via a cannula in the abdominal aorta or common iliac artery and drained via a cannula in the inferior vena cava or common iliac vein. Alternatively, cannulation may be via the femoral vessels where allowed pre‐mortem The descending thoracic aorta and the inferior vena cava are occluded above the diaphragm to confine the circulation to the organs in the abdominal cavity |
Direct (hypothermic) procurement and perfusion of the heart combined with abdominal‐normothermic regional perfusion | DPP with A‐NRP | Cannulae inserted into the abdominal aorta and inferior vena cava or the common iliac vessels for extracorporeal circulation. The descending thoracic aorta is occluded before starting circulation to the abdominal organs. The ascending aorta is clamped distal to a cannula inserted proximally to allow the administration of cold preservation solution and excision of the heart without restarting it in situ |
Thoraco abdominal‐normothermic regional perfusion | TA‐NRP | The extracorporeal circulation is provided by cannulae in the abdominal aorta or common iliac artery and in the right atrium or inferior vena cava. The descending thoracic aorta is not occluded to allow delivery of oxygenated blood to both the thoracic and abdominal organs |
Abbreviations: DCD, donation after circulatory death; A‐NRP, abdominal‐normothermic regional perfusion; TA‐NRP, thoraco‐abdominal‐ normothermic regional perfusion; DPP, direct (hypothermic) procurement and perfusion; NRP, normothermic regional perfusion.