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. 2020 Jul 17;126(19):4341–4352. doi: 10.1002/cncr.33085

TABLE 2.

Patient and Clinical Characteristics of the Entire Study Population (N = 1608)

Characteristics at the Time of BM Diagnosis Entire Population
No. %
Sex
Male 922 57.3
Female 686 42.7
Y of BM diagnosis
1986‐1999 146 9.1
CT imaging at BM diagnosis 80 5.0
MRT imaging at BM diagnosis 66 4.1
2000‐2009 636 40.0
2010‐2019 826 50.9
Symptoms at BM diagnosis
Present 1186 73.8
Absent (diagnosis during screening) 422 26.2
Focal deficits
Present 985 61.3
Motor disorders 486 30.2
Motor disfunction of 1 extremity 205 12.7
Hemiparesis 220 13.7
Facial nerve palsy 61 3.8
Ataxia 95 5.9
Cranial nerve palsy 204 12.7
Hypesthesia 124 7.7
Aphasia 164 10.2
Vertigo 481 29.9
Absent 623 38.7
Signs of increased intracranial pressure
Present 483
Headache 397 24.7
Nausea and emesis 231 14.3
Absent 1125 75.3
Seizures
Present 224 13.9
Generalized seizures 123 7.6
Focal seizures 91 3.1
Generalized and focal seizures 10 0.6
Absent 1384 86.1
Neuropsychological symptoms
Present 233 14.5
Organic brain disorder 125 7.8
Cognitive impairment 87 5.4
Memory disorders 87 5.4
Absent 1375 85.5

Abbreviations: BM, brain metastases; CT, computed tomography; MRI, Magnetic resonance imaging .