Figure 3.

Knockdown of β₂‐AR restrains xenograft growth in vivo. A‐C, PC‐3 cells stably expressing shNC or shβ₂‐AR were injected subcutaneously into the subaxilla of nude mice. Representative images of dissected tumors at the end of the experiment are shown (A), and tumor growth curves (B) and tumor weights (C) of mice were analyzed. D, Representative immunohistochemistry images and quantification of β₂‐AR and Ki‐67 expression in xenografts. Scale bar, 100 μm. β₂‐AR, β₂‐adrenergic receptor [Color figure can be viewed at wileyonlinelibrary.com]