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. 2020 Feb 20;22(7):1239–1246. doi: 10.1002/ejhf.1758

Figure 2.

EJHF-1758-FIG-0002-c

Results from network analysis showing protein–protein interactions for empirically identified markers (orange), predicted markers (blue) and associated pathways (green). ACP5, acid phosphatase 5, Tartrate Resistant; ALCAM, activated leukocyte cell adhesion molecule; CCL2, chemokine (C‐C motif) ligand 2; CCL15, chemokine (C‐C motif) ligand 15; CHI3L1, chitinase‐3‐like protein 1; EGFR, epidermal growth factor receptor; GRN, granulin; HSPG2, heparan sulfate proteoglycan 2; LDLR, low‐density lipoprotein receptor; LGALS3, galectin‐3; MMP2, matrix metalloproteinase 2; MMP3, matrix metalloproteinase 3; PCSK9, proprotein convertase subtilisin/kexin type 9; PDGFA, platelet‐derived growth factor subunit A; SPP1, secreted phosphoprotein 1; TIMP4, tissue inhibitor of metalloproteinase 4.