Table 1.
Patient characteristics
| Variables | All patients (n = 1167) | Split–level typed patients (n = 312) |
|---|---|---|
| Recipient characteristics | ||
| Age at HTx, years, median (IQR) | 53.8 (45.7–60.2) | 56 (45.2–62.3) |
| Male sex | 949 (81.3) | 249 (79.8) |
| Weight, kg, median (IQR) | 75 (66–83) | 77 (67–85) |
| Height, cm, median (IQR) | 174 (168–179) | 174 (168–180) |
| Heart failure etiology | ||
| Dilative cardiomyopathy | 712 (61) | 188 (60.3) |
| Ischemic cardiomyopathy | 373 (32) | 90 (28.8) |
| Congenital heart disease | 25 (2.1) | 15 (4.8) |
| Other | 57 (4.9) | 19 (6.1) |
| Previous cardiac surgery | 447 (38.4) | 130 (41.9) |
| Diabetes mellitus | 231 (19.9) | 58 (18.7) |
| Serum bilirubin, mg/dl, median (IQR) | 0.9 (0.6–1.6) | 0.9 (0.6–1.4) |
| Serum creatinine, mg/dl, median (IQR) | 1.2 (1.0–1.5) | 1.2 (1.0–1.5) |
| Renal replacement therapy | 37 (3.2) | 12 (3.9) |
| Pre–transplant admission status | ||
| At home | 698 (60) | 194 (62.2) |
| Hospitalized | 295 (25.4) | 72 (23.1) |
| ICU | 170 (14.6) | 46 (14.7) |
| VAD support | 150 (12.9) | 62 (19.9) |
| ECMO support | 20 (1.7) | 8 (2.6) |
| IABP support | 2 (0.2) | 0 (0) |
| Mechanical ventilation | 26 (2.2) | 7 (2.2) |
| Infection | 32 (2.8) | 20 (3.2) |
| IMPACT–Score26, median (IQR) | 4 (2–6) | 4.5 (2–7) |
| Donor characteristics | ||
| Age, years, median (IQR) | 35 (24–45) | 38.5 (27–48) |
| Weight, kg, median (IQR) | 75 (67–85) | 77 (70–85) |
| Height, cm, median (IQR) | 175 (170–180) | 176 (170–182) |
| Male sex | 819 (70.2) | 215 (68.9) |
| Cause of death: Trauma | 578 (50) | 139 (45) |
| HTx era | ||
| 1984–1999 | 623 (53.4) | 80 (25.6) |
| 2000–2008 | 265 (22.7) | 81 (26) |
| 2009–2012 | 126 (10.8) | 63 (20.2) |
| 2013–2016 | 153 (13.1) | 88 (28.2) |
| Combined heart‐kidney‐Tx | 16 (1.4) | 6 (1.9) |
| Primary graft dysfunction | 157 (13.5) | 51 (16.4) |
| Immunosuppressive regimen | ||
| Cyclosporin A | 933 (79.9) | 198 (64.3) |
| Tacrolimus | 226 (19.4) | 110 (35.7) |
| Number of amino acid mismatches for HLA‐AB, median (IQR) | 8 (4–12) | 8 (5–13) |
| Number of amino acid mismatches for HLA‐DR, median (IQR) | 5 (2.25–7) | 4 (2–7) |
| Follow–up, years, median (IQR) | 8 (3–15) | 5.8 (2.8–11.7) |
Values are n (%) unless indicated otherwise. ECMO, extracorporeal membrane oxygenation; HLA, human leukocyte antigen; HTx, heart transplantation; IABP, intra‐aortic balloon pump; ICU, intensive care unit; IQR, inter‐quartile range; Tx, transplantation; VAD, ventricular assist device.