Table 2.
One‐year graft survival. Univariate and multivariable Cox proportional hazards regression models
| AAMM | Univariate | Multivariable†, ‡ | ||||
|---|---|---|---|---|---|---|
| HR | CI (95%) | P‐value | HR | CI (95%) | P‐value | |
| HLA–AB – all patients | ||||||
| Continuous* | 1.03 | 0.91–1.17 | 0.59 | 1.04 | 0.92–1.18 | 0.55 |
| HLA–AB – split–level typed patients | ||||||
| Continuous* | 1.07 | 0.84–1.36 | 0.57 | 1.07 | 0.86–1.34 | 0.53 |
| HLA–DR – all patients | ||||||
| Continuous* | 1.14 | 1.01–1.28 | 0.03 | 1.11 | 0.99–1.26 | 0.08 |
| HLA–DR – split–level typed patients | ||||||
| Continuous* | 1.22 | 0.99–1.51 | 0.06 | 1.19 | 0.97–1.47 | 0.10 |
Bold values are P‐values considered statistically significant, with a value P < 0.05.
*
log2‐transformed; HRs refer to a doubling of the HLA AAMM number.
†
All Patients adjusted for: transplant era (1984–1999 vs 2000–2008, 1984–1999 vs 2009–2012, 1984–1999 vs 2013–2016), primary graft dysfunction, IMPACT score26, donor age, preoperative admission to intensive care unit vs non‐ICU, previous cardiac surgery.
‡
Split‐level Typed Patients adjusted for: transplant era, primary graft dysfunction.