. 2020 Sep 2;52(8):1353–1365. doi: 10.1111/apt.16060

Table 4.

Incidence of gastrointestinal infections of special interest in patients with UC or CD

Parameter	Ulcerative colitis (N = 894)		Crohn's disease (N = 1349)
Parameter	n (%)	Incidence/1000 person‐years (95% CI) ^a	n (%)	Incidence/1000 person‐years (95% CI) ^a
Gastrointestinal infections of special interest	122 (13.6)	46.9 (38.3, 55.6)	162 (12.0)	46.1 (38.8, 53.4)
Abdominal and gastrointestinal infections (pathogen unspecified) ^b	92 (10.3)	34.9 (27.6, 42.3)	141 (10.5)	39.6 (32.9, 46.3)
Clostridium infections ^c	26 (2.9)	9.1 (5.6, 12.6)	21 (1.6)	5.4 (3.1, 7.8)
Campylobacter infections ^d	9 (1.0)	3.1 (1.1, 5.2)	8 (<1)	2.1 (0.6, 3.5)
Shigella infections ^e	0	0	1 (<1)	0.3 (0, 0.8)
Yersinia infections ^f	1 (<1)	0.3 (0, 1.0)	0	0
Bacterial infections (bacteria unspecified) ^g	0	0	1 (<1)	0.3 (0, 0.8)

Abbreviation: CI, confidence interval; MedDRA, Medical Dictionary for Regulatory Activities.

^{^a}

Time‐adjusted incidence rate per 1000 person‐years = (number of patients experiencing an adverse event of interest/total person time in years) × 1000.

^{^b}

MedDRA preferred terms: gastroenteritis, diarrhoea infectious, gastrointestinal infection, enteritis infectious, enterocolitis infectious and gastric infection.

^{^c}

MedDRA preferred terms: Clostridium difficile colitis, Clostridial infection and Clostridium colitis.

^{^d}

MedDRA preferred terms: Campylobacter gastroenteritis, Campylobacter intestinal infection and Campylobacter infection.

^{^e}

MedDRA preferred term gastroenteritis shigella.

^{^f}

MedDRA preferred term gastroenteritis yersinia.

^{^g}

Bacterial infections represent MedDRA preferred term gastroenteritis bacterial.