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X‐ray structural analysis study of the guest binding pockets of 1P1P (a), 1P2P (b), and 2P1P (c) in CMOM‐3S. CMOM‐3S discriminates between similar substrates. The color of the Connolly surface represents the element that generates the corresponding part of the surface: C orange, O red, N blue, F cyan, H white. The carbon atoms of the substrates are colored magenta. The yellow, green, and red arrows indicate the aromatic, hydrophobic, and hydrophilic surface of the CMOM, respectively.
