Table 1.
Pair | ID | Age | Gender | RIN | PMI (hours) | Toxicology | Tissue preservation | Matter type used for qPCR |
---|---|---|---|---|---|---|---|---|
Controls | ||||||||
1 | AN14757 | 24 | M | 7.8 | 21.33 | Frozen | WM | |
2 | AN07176 | 21 | M | 7.6 | 29.91 | Frozen | WM, GM | |
3 | AN07444 | 17 | M | 6.1 | 30.75 | Sertraline | Frozen | WM |
4 | 5408 | 6 | M | 5.8 | 16 | Frozen | WM | |
5 | 4848 | 16 | M | 7.5 | 15 | Frozen | WM, GM | |
6 | 5342 | 22 | M | 8.0 | 14 | Frozen | WM, GM | |
7 | 5079 | 33 | M | 5.3 | 16 | Ethanol | Frozen | WM, GM |
8 | M3231M | 37 | M | 4.9 | 24 | Frozen | WM, GM | |
9 | AN12137 | 31 | M | 4.5 | 32.92 | Frozen | WM, GM | |
10 | AN03217 | 19 | M | 5.3 | 18.58 | Frozen | WM, GM | |
11 | AN00544 | 17 | M | 5.8 | 28.92 | Frozen | WM, GM | |
12 | AN17425 | 16 | M | 6.8 | 26.16 | Frozen | WM, GM | |
13 | 4590 | 20 | M | 6.8 | 19 | Frozen | WM, GM | |
14 | 4670 | 4 | M | 6.2 | 17 | Frozen | WM, GM | |
17 | 4787 | 12 | M | 5.7 | 15 | Montelukast, Albuterol, Prednisone, Loratidine | Frozen | GM |
18 | 1105 | 16 | M | 7.8 | 17 | Frozen | GM | |
19 | 4334 | 12 | M | 5.7 | 15 | Frozen | GM | |
Mean | 19.24 | 6.3 | 20.97 | |||||
SEM | 2.12 | 0.3 | 1.56 | |||||
ASD | ||||||||
1 | AN04166 | 24 | M | 8.1 | 18.51 | Frozen | WM | |
2 | AN03935 | 19 | M | 7.0 | 28 | Frozen | WM, GM | |
3 | AN02987 | 15 | M | 6.7 | 30.83 | Frozen | WM | |
4 | 5144 | 7 | M | 8.0 | 3 | Frozen | WM | |
5 | 5302 | 16 | M | 4.8 | 20 | Risperidone, Fluvoxamine, Clonidine, Insulin | Frozen | WM, GM |
6 | 5176 | 22 | M | 5.1 | 18 | Risperdal | Frozen | WM, GM |
7 | 5297 | 33 | M | 2.5 | 50 | Quetiapine, Fluoxetine, Divalproex Sodium, ziprasidone | Frozen | WM, GM |
8 | 5027 | 37 | M | 4.7 | 26 | Risperidone, Fluvoxamine | Frozen | WM, GM |
9 | AN11989 | 30 | M | 5.7 | 16.06 | Frozen | WM, GM | |
10 | AN07817 | 19 | M | 4.5 | 14.83 | Frozen | WM, GM | |
11 | AN00764 | 20 | M | 5.9 | 23.66 | Minocycline | Frozen | WM, GM |
12 | AN04682 | 15 | M | 5.6 | 23.23 | Frozen | WM, GM | |
13 | 4999 | 20 | M | 7.0 | 14 | Frozen | WM, GM | |
14 | 5308 | 4 | M | 7.0 | 21 | Frozen | WM, GM | |
17 | 5565 | 12 | M | 7.0 | 22 | Frozen | GM | |
18 | 5403 | 16 | M | 6.6 | 35 | Frozen | GM | |
19 | 5334 | 11 | M | 5.1 | 15 | Frozen | GM | |
Mean | 18.88 | 6.0 | 22.30 | |||||
SEM | 2.11 | 0.3 | 2.48 | |||||
P‐valuea | 0.906 | 0.403 | 0.654 |
ID, identification number; RIN,, RNA integrity number; PMI,, postmortem interval; qPCR,, quantitative real‐time polymerase chain reaction; WM,, white matter; GM,, gray matter.
P‐value = results of an independent t‐test comparing control and ASD groups, statistically significant when P < 0.05.