Table 3. Diagnostic characteristics for prehospital modified HEART Pathway and core-lab-prehospital modified HEART Pathway for 30-day MACE and Death/MI.
| 30-day MACE | 30-day Death/MI | ||||
|---|---|---|---|---|---|
| PMHP | Core-Lab-PMHP | PMHP | Core-Lab-PMHP | ||
| High Risk | Specificity (95%CI) | 96.6% (94.0–98.3%) | 92.1% (87.9–95.3%) | 96.6% (94.0–98.3%) | 92.3% (88.1–95.4%) |
| PPV (95%CI) | 60.7% (40.6–78.5%) | 66.7% (52.5–78.9%) | 60.7% (40.6–78.5%) | 66.7% (52.5–78.9%) | |
| +LR (95%CI) | 6.704 (3.279–13.705) | 7.897 (4.852–12.850) | 7.175 (3.517–14.640) | 8.630 (5.328–13.977) | |
| Low Risk | Sensitivity (95%CI) | 90.5% (81.5–96.1%) | 100% (93.8–100%) | 90.0% (80.5–95.9%) | 100% (93.4–100%) |
| NPV (95%CI) | 94.4% (88.7–97.7%) | 100% (95.2–100%) | 94.4% (88.7–97.7%) | 100% (95.2–100%) | |
| -LR (95%CI) | 0.260 (0.126–0.533) | 0 (0-NA) | 0.278 (0.136–0.569) | 0 (0-NA) | |
PMHP—prehospital modified HEART Pathway, MACE—major adverse cardiac events, NPV—negative predictive value, PPV—positive predictive value, -LR—negative likelihood ratio, +LR positive likelihood ratio, POC—point of care.