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. 2020 Oct 7;15(10):e0240169. doi: 10.1371/journal.pone.0240169

Table 2. Next generation sequencing results for PDX passages.

SNPs from P0-P3
Gene Conserved Non-Conserved Total SNPs % Conserved
EGFR 10 2 12 83.33
KRAS 5 0 5 100.0
FGFR1 9 4 13 69.23
PIK3CA 9 2 11 81.82
PTEN 2 0 2 100.0
ALK 1 7 8 12.50
EML4 0 1 1 0.0
ERBB2 0 2 2 0.0
AKT1 11 1 12 91.67
MET 1 0 1 100.0
PPP2R1A 17 1 18 94.44
PPP2R1B 2 0 2 100.0