Table 2. Next generation sequencing results for PDX passages.
SNPs from P0-P3 | ||||
---|---|---|---|---|
Gene | Conserved | Non-Conserved | Total SNPs | % Conserved |
EGFR | 10 | 2 | 12 | 83.33 |
KRAS | 5 | 0 | 5 | 100.0 |
FGFR1 | 9 | 4 | 13 | 69.23 |
PIK3CA | 9 | 2 | 11 | 81.82 |
PTEN | 2 | 0 | 2 | 100.0 |
ALK | 1 | 7 | 8 | 12.50 |
EML4 | 0 | 1 | 1 | 0.0 |
ERBB2 | 0 | 2 | 2 | 0.0 |
AKT1 | 11 | 1 | 12 | 91.67 |
MET | 1 | 0 | 1 | 100.0 |
PPP2R1A | 17 | 1 | 18 | 94.44 |
PPP2R1B | 2 | 0 | 2 | 100.0 |