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. 2020 Oct 7;15(10):e0238617. doi: 10.1371/journal.pone.0238617

Table 2. Clinical and laboratory characteristics based on 2014 US CDC diagnostic criteria.

Definite Probable Total
9 16 25
    Male 8 11 19
    Indigenous 3 9 11
    HIV 2 0 2
Clinical Diagnoses n = 8 n = 16 n = 24
Meningitis 0 0 0
Ocular 1 0 1
Meningovascular 1 1 2
Dementia 4 10 14
Psychosis 1 2 3
Tabes Dorsalis 1 2 3
Seizures 2 2 4
Laboratory
Number of reactive serum RPR 9 10 19
Median RPR titre 1:128 (1:2–1:512) 1:4 (1:1–1:16) 1:8 (1:1–1:512)
Number of CSF examinations 9 16 25
Number of positive CSF VDRL (≥ 1:1) 9 0 9
Number of reactive CSF TPPA 8 2 10
Number of reactive CSF FTA 8 4 12
Number with high WCC in CSF (WCC > 5 cell/microL) 5 (median 26cell/microL, range 7-45cell/microL) 2 (range 10-21cell/microL) 7 (median 21 cell/microL, range 7–45 cell/microL)
Number with high CSF Protein (Protein > 0.50 mg/L) 6 (median 1.08mg/L, range 0.68–1.37mg/L) 16 (median 0.725mg/L, range 0.57–1.37mg/L) 22 (median 0.77mg/L, range 0.57–1.37mg/L)
Management n = 9 n = 16 n = 25
Treatment for NS 9 6 15