Skip to main content
. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: J Surg Res. 2020 Mar 12;251:239–247. doi: 10.1016/j.jss.2020.01.028

Figure 2. Increased neutrophil infiltration in AAA tissue.

Figure 2.

Comparative histology performed on days 7 and 14 indicates that elastase-treated WT mice have a marked increase in neutrophil (PMN) infiltration, a decrease in smooth muscle cell α-actin (SM-αA) expression, as well as increase in elastic fiber disruption (Verhoeff-Van Gieson staining for elastin) compared to deactivated elastase-treated (control) mice, respectively. Quantification of histologic grading indicates a significant increase in neutrophil infiltration, decrease in SM-αA expression and increase in elastic fiber disruption in elastase-treated aortic tissue on days 7 and 14 compared to controls. Arrows indicate areas of immunostaining. *P<0.005 vs. Control Day 7; #P<0.0005 vs. Control Day 14; ns, not significant; n=5 mice/group.