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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: J Surg Res. 2020 Mar 12;251:239–247. doi: 10.1016/j.jss.2020.01.028

Figure 4. Increased uptake of c-FLFLF in AAA by SPECT/CT imaging of mice.

Figure 4.

(A) SPECT/CT imaging using 99mTc-cFLFLF demonstrated an increase in c-FLFLF uptake (shown by arrows) in elastase-treated mice (AAA) compared to controls on day 14, signifying increased aortic inflammation relative to aneurysms. CT and SPECT scans were utilized to image the animal as it moved along the axis of rotation, allowing for combination of CT and SPECT images using stored offset parameters. (B) A significant increase in 99mTc-cFLFLF radioactivity was observed in harvested aortic tissue from elastase-treated mice compared to controls. *P<0.05 vs. control; n=4–5 mice/group.