Table 2.
Linear mixed-effects models of Dm, with and without quadratic age terms. Values represent coefficients (s.e.). Models include a random intercept for individual to account for subjects with multiple observations. Models were weighted by the number of biomarkers measured for each observation. * = 0.05, ** = 0.01, *** = 0.001.
| model 1 | model 2 | |
|---|---|---|
| age (standardized) | 0.130*** | 0.175*** |
| (0.011) | (0.009) | |
| age2 (standardized) | 0.051*** | |
| (0.007) | ||
| sex (ref = female) | 0.006 | 0.032* |
| (0.017) | (0.014) | |
| number of biomarkers | 0.026*** | 0.024*** |
| (0.001) | (0.001) | |
| age × sex | –0.034* | −0.005 |
| (0.016) | (0.013) | |
| age2 × sex | 0.035** | |
| (0.011) | ||
| intercept | −0.302*** | −0.229*** |
| (0.018) | (0.015) | |
| AICc | 57 566 | 57 697 |
| number of observations | 22 115 | |