A‐C, A hairy green fluorescent mouse (A), a hairless green fluorescent mouse (B) and a newborn hairless green fluorescent mouse (C) under light, respectively. D, For the hairy mouse, only the auricle, the claw and tip of the nose presented green, as their white hair covered most of their body surface. E, F, Green fluorescence could be detected under illumination of a blue‐light‐emitting flashlight with a central peak of 480 nm, in which the whole body of the hairless mice emitted green fluorescence. G, Relative fluorescent value in different locations of the brain was detected by fluorescence spectrophotometer. The differences between groups were considered significant at P < 0.001 and were analyzed with one‐way ANOVA followed by Student‐Newman‐Keuls tests. aDifferences with cerebellum. H, RT‐PCR analysis of enhanced green fluorescent protein (EGFP) expression in different organs. Relative expression of EGFP in muscle and heart were significantly higher than in other organs. The differences between groups were considered significant at P < 0.05 and were analyzed with one‐way ANOVA followed by Student‐Newman‐Keuls tests. aDifferences with heart; bdifferences with muscle. I, EGFP expression in different locations of the brain was detected by RT‐PCR. The differences between groups were considered significant at P < 0.001 and were analyzed with one‐way ANOVA followed by Student‐Newman‐Keuls tests. aDifferences with cerebellum