FIGURE 4.

High lncARSR promotes liver metastasis of colorectal cancer (CRC) cells in nude mice. A, Representative hematoxylin‐eosin (HE) staining of liver metastasis in nude mice after 4 wk spleen injection of CRC cells. The black arrow indicates the metastatic node and the green arrow points to a normal liver cell (scale bar, 200 μm). B, C, Nude mice were separated into 4 groups (n = 5/group) and injected with lncARSR‐overexpressed Caco‐2 cells, lncARSR‐silenced HCT‐8, or their respective controls. The number of metastatic colonies in HE‐stained images of liver tissue was counted. **P < .01