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. 2020 Aug 4;111(10):3835–3844. doi: 10.1111/cas.14573

TABLE 2.

Comparison of predictive performance between risk prediction models for upper aerodigestive tract cancer based on case‐cohort subjects from the baseline survey

C‐index (95% confidence interval) IDI Continuous NRI Categorical NRI a
Model
Environmental model 0.67 (0.52‐0.80) Reference Reference Reference
Gene‐environment interaction model 0.71 (0.57‐0.84) 0.0036 0.033 0.13

Abbreviations: IDI, integrated discrimination improvement; NRI, net reclassification improvement.

a

Risk category of NRI was defined as <0.25%, ≥0.25%, and <1% and ≥1% 10‐y absolute risk of developing upper aerodigestive tract cancer.