TABLE 4.

Ten‐year absolute risk (95% confidence interval) (%) of developing upper aerodigestive tract cancer for men according to risk factor profile based on case‐cohort subjects from the baseline survey

Age group	Smoking status	Combination of alcohol consumption and ALDH2 genotype
		Nondrinkers/<5 d per week or <23 g of ethanol/day + Glu/Glu Nondrinkers/<5 d per week or <23 g of ethanol/day + Glu/Lys + Lys/Lys	≥5 d per week and ≥23 g ethanol/day + Glu/Glu	≥5 d per week and ≥23 g ethanol/day + Glu/Lys + Lys/Lys
<50 y old	Never smoker	0.09 (0.05, 0.18)	0.15 (0.07, 0.31)	0.55 (0.23, 1.31)
	Past smoker	0.19 (0.10, 0.37)	0.30 (0.17, 0.55)	1.15 (0.57, 2.32)
	Current smoker	0.27 (0.16, 0.47)	0.43 (0.25, 0.74)	1.63 (0.86, 3.10)
50‐<60 y old	Never smoker	0.21 (0.11, 0.40)	0.33 (0.16, 0.66)	1.24 (0.55, 2.79)
	Past smoker	0.43 (0.23, 0.80)	0.68 (0.40, 1.16)	2.58 (1.38, 4.82)
	Current smoker	0.61 (0.40, 0.93)	0.96 (0.65, 1.42)	3.65 (2.22, 6.01)
≥60 y old	Never smoker	0.34 (0.19, 0.62)	0.54 (0.27, 1.11)	2.06 (0.94, 4.50)
	Past smoker	0.71 (0.41, 1.23)	1.13 (0.65, 1.94)	4.27 (2.38, 7.65)
	Current smoker	1.01 (0.64, 1.58)	1.59 (0.95, 2.66)	6.05 (3.49, 10.47)

Abbreviation: ALDH2: aldehyde dehydrogenase 2.