TABLE 4.

Odds ratios (ORs) and 95% confidence intervals (CI) of colorectal adenoma according to total sugar intake by site, size, and number of adenomas

	Quartile category				P trend
	Q1	Q2	Q3	Q4
Adenoma site
Proximal
Case (n)	94	81	99	108
OR (95% CI) 1	1.00 (Ref.)	0.88 (0.60‐1.30)	1.12 (0.75‐1.69)	1.29 (0.82‐2.03)	.16
OR (95% CI) 2	1.00 (Ref.)	0.93 (0.63‐1.38)	1.17 (0.78‐1.77)	1.32 (0.84‐2.09)	.14
Distal
Case (n)	85	63	64	51
OR (95% CI)1	1.00 (Ref.)	0.96 (0.63‐1.46)	1.03 (0.65‐1.62)	0.97 (0.57‐1.67)	1.00
OR (95% CI) 2	1.00 (Ref.)	0.99 (0.65‐1.52)	1.06 (0.67‐1.68)	1.01 (0.59‐1.74)	.89
Rectal
Case (n)	22	25	17	17
OR (95% CI)1	1.00 (Ref.)	1.68 (0.86‐3.29)	1.33 (0.61‐2.90)	1.64 (0.68‐3.95)	.38
OR (95% CI) 2	1.00 (Ref.)	1.77 (0.89‐3.50)	1.32 (0.60‐2.93)	1.75 (0.72‐4.30)	.35
Adenoma size (mm)
≥5
Case (n)	96	89	72	68
OR (95% CI)1	1.00 (Ref.)	1.10 (0.75‐1.62)	0.95 (0.61‐1.47)	1.09 (0.66‐1.80)	.92
OR (95% CI) 2	1.00 (Ref.)	1.14 (0.77‐1.69)	0.95 (0.62‐1.47)	1.11 (0.67‐1.84)	.90
<5
Case (n)	107	85	110	111
OR (95% CI)1	1.00 (Ref.)	0.90 (0.62‐1.31)	1.20 (0.81‐1.78)	1.31 (0.84‐2.02)	.12
OR (95% CI) 2	1.00 (Ref.)	0.96 (0.65‐1.40)	1.29 (0.86‐1.92)	1.37 (0.87‐2.14)	.087
Adenoma number
≥2
Case (n)	92	68	75	78
OR (95% CI)1	1.00 (Ref.)	0.91 (0.60‐1.38)	1.15 (0.73‐1.79)	1.53 (0.92‐2.54)	.075
OR (95% CI) 2	1.00 (Ref.)	0.94 (0.62‐1.44)	1.14 (0.73‐1.79)	1.53 (0.92‐2.54)	.086
1
Case (n)	111	106	107	101
OR (95% CI)1	1.00 (Ref.)	1.02 (0.71‐1.46)	1.04 (0.71‐1.53)	1.01 (0.65‐1.56)	.96
OR (95% CI) 2	1.00 (Ref.)	1.08 (0.75‐1.56)	1.10 (0.74‐1.63)	1.06 (0.68‐1.65)	.80

Model 1: Adjusted for age, sex, screening period, physical activity, smoking status, alcohol use, family history of colorectal cancer, nonsteroidal antiinflammatory drug use, intake of total calories, fiber, and calcium. Model 2: Further adjusted for body mass index and diabetes history.

Abbreviation: Ref., reference.