Table 1.
Group | Risk score | Variables | Patients (n = 257) | MST (d) | Crude HR (95% CI) | Crude P | Adjusted HR (95% CI) | Adjusted P c |
---|---|---|---|---|---|---|---|---|
Age (y) | ||||||||
A | Low risk | ≤65 | 84 | 2694 | 1 | 1 | ||
B | Low risk | >65 | 45 | 1953 | 2.025 (1.071‐3.830) | .030 | 1.848 (0.959‐3.558) | .066 |
C | High risk | ≤65 | 73 | 1970 | 1.905 (1.062‐3.417) | .031 | 2.128 (1.172‐3.861) | .013 |
D | High risk | >65 | 55 | 1049 | 4.918 (2.784‐8.689) | <.001 | 4.895 (2.741‐8.742) | <.001 |
Residual tumor a | ||||||||
a | Low risk | R0 | 77 | NA | 1 | 1 | ||
b | Low risk | R1/R2/Rx | 51 | 1953 | 2.939 (1.532‐5.640) | .001 | 2.297 (1.159‐4.553) | .014 |
c | High risk | R0 | 76 | 1649 | 2.519 (1.347‐4.712) | .004 | 2.383 (1.266‐4.485) | .007 |
d | High risk | R1/R2/Rx | 52 | 1049 | 6.435 (3.427‐12.084) | <.001 | 5.454 (2.853‐10.425) | <.001 |
Tumor multifocal b | ||||||||
I | Low risk | Single | 97 | NA | 1 | 1 | ||
II | Low risk | Multiple | 23 | 2034 | 2.233 (1.130‐4.414) | .021 | 1.705 (0.834‐3.484) | .143 |
III | High risk | Single | 91 | 1466 | 2.454 (1.468‐4.100) | .001 | 2.353 (1.404‐3.944) | .001 |
IV | High risk | Multiple | 26 | 1366 | 3.446 (1.734‐6.848) | <.001 | 3.289 (1.644‐6.579) | .001 |
Abbreviations: CI, confidence interval; HR, hazard rate; MST, median survival time; NA, not available.
Information of residual tumor was unavailable in one patients.
Information of tumor multifocal was unavailable in 20 patients.
Adjusted for age, residual tumor, and tumor multifocal.