TABLE 2.
Univariate analysis of the clinicopathological features and overall survival of patients with spinal cord astrocytomas
| Variable | All patients | Low‐grade | High‐grade | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P‐value | |
| Age (y) | 1.03 (1.01‐1.05) | .007 | 1.03 (0.97‐1.09) | .323 | 1.00 (0.98‐1.03) | .763 |
| Sex (male) | 0.60 (0.33‐1.08) | .089 | 1.04 (0.20‐5.39) | .959 | 0.70 (0.37‐1.33) | .275 |
| WHO grade (I‐IV) | 3.33 (2.24‐4.96) | <.001 | 33.04 (0.03‐44265.88) | .341 | 4.06 (1.23‐13.42) | .021 |
| Location (C, C‐T, T, T‐L) | 0.92 (0.70‐1.22) | .574 | 1.00 (0.49‐2.04) | .989 | 0.86 (0.64‐1.16) | .325 |
| Segment length | 1.13 (0.96‐1.34) | .152 | 0.87 (0.53‐1.43) | .586 | 1.19 (0.99‐1.44) | .066 |
| Presurgery MMS (1‐4) | 2.77 (1.87‐4.10) | <.001 | 1.70 (0.61‐4.79) | .312 | 1.99 (1.20‐3.31) | .008 |
| Resection (GTR, STR, PR) | 1.78 (1.28‐2.47) | .001 | 2.89 (1.24‐6.74) | .014 | 1.26 (0.86‐1.83) | .231 |
| Radiotherapy | 0.82 (0.40‐1.68) | .586 | 0.78 (0.14‐4.32) | .777 | 0.69 (0.31‐1.53) | .357 |
| Chemotherapy | 1.86 (0.95‐3.63) | .070 | 0.89 (0.10‐7.59) | .911 | 1.05 (0.51‐2.19) | .890 |
| Ki‐67 expression (≥10%) | 6.33 (3.09‐12.93) | <.001 | 1.90 (0.37‐9.79) | .445 | 3.47 (1.33‐9.02) | .011 |
Significance of bold values P < .05.
Abbreviations: C, cervical; CI, confidential interval; C‐T, cervicothoracic; GTR, gross total resection; MMS, Modified McCormick Scale; PR, partial resection or open biopsy; STR, subtotal resection; T, thoracic; T‐L, thoracolumbar.