Table 3.
Demographics and Perioperative Characteristics of HTx Recipients Stratified by RRT
| Non-AKI without RRT (n = 62) |
AKI without RRT (n = 17) | AKI with RRT (n = 16) |
P value | |
|---|---|---|---|---|
| Demographic data | ||||
| Age, years | 53.87 ± 11.94 | 52.24 ± 14.63 | 58.19 ± 7.77 | 0.597 |
| < 60 | 36(58.06) | 10(58.82) | 9(56.25) | 0.988 |
| ≥ 60 | 26(41.94) | 7(41.18) | 7(43.75) | |
| Sex, men, n (%) | 5(80.65) | 17(100) | 14(87.50) | 0.135 |
| BMI (kg/m2) | 24.14 ± 3.51 | 25.11 ± 4.52 | 25.47 ± 4.23 | 0.368 |
| History of alcohol | 21(33.87) | 2(11.76) | 6(37.50) | 0.176 |
| History of smoking | 40(64.52) | 13(76.47) | 10(62.50) | 0.616 |
| Hypertension | 22(35.48) | 9(52.94) | 8(50.00) | 0.318 |
| Diabetes mellitus | 20(32.26) | 6(35.29) | 8(50.00) | 0.422 |
| Chronic kidney disease | 10(16.13) | 3(16.13) | 7(43.75) | 0.052 |
| Pretransplant characteristics | ||||
| DCM | 30(48.39) | 5(29.41) | 3(18.75) | 0.062 |
| CAD | 14(22.58) | 5(29.41) | 8(50.00) | 0.097 |
| Valve disease | 10(16.13) | 2(11.76) | 3(18.75) | 0.854 |
| Pre-PCI | 4(6.45) | 5(29.41) | 2(12.50) | 0.033* |
| ICD implantation | 3(4.84) | 0(0) | 0(0) | 0.442 |
| LVAD implantation | 0(0) | 1(5.88) | 0(0) | 0.098 |
| Cardiac tumor | 1(1.61) | 0(0) | 0(0) | 0.764 |
| EF pre-HTx (%) | 27(22,30) | 28(25,30) | 28.5(24.5,33.5) | 0.571 |
| Creatinine (mg/dL) | 1.14(0.95,1.27) | 1.14(1.00,1.19) | 1.25(1.04,1.51) | 0.244 |
| GFR (ml/min/1.73 m2) | 38.05(29.68,46.23) | 39.18(35.39,47.80) | 37.36(24.10,40.43) | 0.183 |
| < 30 | 16(25.81) | 2(11.76) | 7(43.75) | 0.189 |
| 30–59 | 40(64.52) | 12(70.59) | 9(56.25) | |
| ≥ 60 | 6(9.68) | 3(17.65) | 0(0) | |
| Intraoperative characteristics | ||||
| CPB duration (min) | 209(180,240) | 210(210,240) | 269(232.5297.5) | 0.0088* |
| Blood transfusion (ml) | 1440(1000,2100) | 1440(1000,1812) | 1500(1300,2625) | 0.499 |
| Infusion (ml) | 1800(1300,2220) | 1980(1400,2950) | 2055(1285,3025) | 0.275 |
| Blood loss (ml) | 1000(1000,2000) | 1000(1000,2500) | 2200(1300,3350) | 0.0298* |
| Urine volume (ml) | 2000(1300,2700) | 1500(1000,2000) | 1100(710,2000) | 0.0021* |
| IABP/ECMO | 1(1.61) | 0(0) | 5(31.25) | <.0001* |
| Postoperative characteristics | ||||
| Urine volume | ||||
| 1st Day after operation | 2200(2030,2795) | 2470(2100,3010) | 1597.5(521,2214) | 0.0016* |
| 2nd Day after operation | 2197.5(1875) | 2130(1800,2465) | 1253.5(145,2087.5) | 0.0020* |
| 3rd Day after operation | 2180(2005,2615) | 2090(2000,2265) | 1365(75,2112.5) | 0.0002* |
| Mechanical ventilation (min) | 1020(780,2080) | 960(783,1380) | 3090(1550,6141) | 0.0033* |
| Time from operation to discharge (days) | 25(22,30) | 28(24,34) | 38(24.5,64) | 0.029* |
| Death | 7(11.29) | 0(0) | 8(50.00) | 0.0001* |
| Mortality in hospital | 4(6.45) | 0(0) | 7(43.75) | <.0001* |
| Death within 1 year | 3(4.84) | 0(0) | 0(0) | 0.438 |
| Follow-up days | 658.5(382,1162) | 954(489,2336) | 261(24.5736.5) | 0.0028* |
* P < 0.05; ANOVA was applied to the BMI variable because of its normal distribution. The Kruskal-Wallis test was used to compare other variables