Table 5.

Predictors of 14-day mortality in children with Pseudomonas aeruginosa bloodstream infection

Variable	Unadjusted OR (95% confidence interval)	P-value	Adjusted OR (95% confidence interval)	P value
Age category N = 91
< 1 year	1		_
≥ 1 year	0.66 (0.23–1.93)	0.45
Weight N = 88
Normal weight	1
Moderate or severe underweight	0.44 (0.15–1.32)	0.10	1.60 (0.330–7.803)	0.557
Admission in a health care facility 28 days prior to current hospitalisation	0.80 (0.27–2.4)	0.79	_
Chronic disease (excluding HIV) N = 80	1.2 (0.24–6.13)	0.827	_
HIV status
HIV-uninfected	1
HIV-infected	1.34 (0.32–5.68)	0.70	_
HIV status unknown	0.89 (0.22–3.62)	0.87
Nature of infection
IPOA	1
HAI	0.202 (0.066–0.619)	0.005	0.083 (0.01–0.60)	0.013
MDR, XDR or PDR isolates	1.05 (0.30–3.61)	0.945	_
Appropriate empiric antibiotic	0.19 (0.06–0.63)	0.007	0.23 (0.07–0.82)	0.023
Presence of a central venous assess device	1.5(0.46–5.06)	0.495	–
Burn wounds	2.24 (0.47–10.77)	0.315	_
Septic shock	3.29 (1.05–10.23)	0.040	2.27 (0.41–12.55)	0.346
Presence of any organ dysfunction	1.97(0.61–6.44)	0.261	–
Anaemia	1.47 (0.43–4.99)	0.540	–
Surgery during current admission	1.96 (0.64–6.0)	0.235	–
Presence of a central venous access device	1.52(0.46–5.06)	0.495	–
ICU management
Patient in the ICU prior to PABSI diagnosis	0.43 (0.15–1.25)	0.101	0.04 (0.005–0.365)	0.004
Patient requiring ICU care after PABSI diagnosis	1.21 (0.399–3.670)	0.737	–
Number of antipseudomonal antibiotics used as definitive therapy
1 antipseudomonal antibiotic	1
2 or more antipseudomonal antibiotics	1.236 (0.345–4.430)	0.745

OR Odds ratio, HAI Healthcare-associated infection, IPOA Infection present on admission, MDR Multidrug-resistant, XDR Extensively drug-resistant, PDR Pan drug-resistant