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. 2020 Oct 6;20:482. doi: 10.1186/s12935-020-01585-1

Fig. 1.

Fig. 1

Copy-number alterations (CNAs) and cross-resistance and –sensitivity to tyrosine kinase inhibitors (TKIs). a Reproduced from Genomics of Drug Sensitivity in Cancer (GDSC) dataset, shown was Venn diagram of each CNAs (GDSC labels and corresponding cytobands) with significant sensitivity or resistance to TKIs in pan-cancer cells; b Reproduced from the Cancer Genome Atlas (TCGA) renal clear cell carcinoma (KIRC) dataset, shown was frequency of CNAs with queried genes in brackets and sensitivity profile in GDSC dataset