Table 1.
Delirium (n = 49) |
No delirium (n = 64) |
P-value | |
---|---|---|---|
Age (years), mean (SD) | 80.76 (11.90) | 81.81 (8.25) | 0.60‡ |
Male sex, n (%) | 28 (57) | 34 (53) | 0.81* |
Charlson comorbidity index, mean (SD) | 3.14 (2.02) | 2.92 (2.35) | 0.59‡ |
Karnofsky Performance Status, mean (SD) | 39.59 (20.61) | 48.44 (25.02) | 0.04‡ |
Number of drugs, mean (SD) | 7.04 (3.26) | 6.14 (3.95) | 0.19‡ |
Number of drugs with psychotropics, mean (SD) | 10.02 (3.78) | 8.66 (4.11) | 0.07‡ |
Psychotropics use, n (%) | |||
Antipsychotics | 33 (67) | 39 (61) | 0.61* |
Benzodiazepine or Z-drugs | 12 (24) | 13 (20) | 0.76* |
Ramelteon or suvorexant | 41 (84) | 55 (86) | 0.95* |
Antidepressant | 3 (6) | 2 (3) | 0.65† |
Other drugs | 19 (39) | 18 (28) | 0.32* |
Other drugs included anti-dementia drugs, valproic acid, Yokukansan
*, Chi-squared test; †, Fisher’s exact test; ‡, Student’s t-test