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. 2020 Oct 6;14:25. doi: 10.1186/s13030-020-00199-3

Table 1.

Patient characteristics (N = 113)

Delirium
(n = 49)
No delirium
(n = 64)
P-value
Age (years), mean (SD) 80.76 (11.90) 81.81 (8.25) 0.60
Male sex, n (%) 28 (57) 34 (53) 0.81*
Charlson comorbidity index, mean (SD) 3.14 (2.02) 2.92 (2.35) 0.59
Karnofsky Performance Status, mean (SD) 39.59 (20.61) 48.44 (25.02) 0.04
Number of drugs, mean (SD) 7.04 (3.26) 6.14 (3.95) 0.19
Number of drugs with psychotropics, mean (SD) 10.02 (3.78) 8.66 (4.11) 0.07
Psychotropics use, n (%)
 Antipsychotics 33 (67) 39 (61) 0.61*
 Benzodiazepine or Z-drugs 12 (24) 13 (20) 0.76*
 Ramelteon or suvorexant 41 (84) 55 (86) 0.95*
 Antidepressant 3 (6) 2 (3) 0.65
 Other drugs 19 (39) 18 (28) 0.32*

Other drugs included anti-dementia drugs, valproic acid, Yokukansan

*, Chi-squared test; , Fisher’s exact test; , Student’s t-test