Table 2.

Selection criteria for studies to be included in systematic review of therapeutic outcomes of multi-drug-resistant tuberculosis and their predictors in adults receiving integrated treatment of tuberculosis and human immuno-deficiency virus in low- and middle-income countries

Item	Inclusion criteria	Exclusion criteria
Population	Studies involving adults who are co-infected with MDR-TB and HIV in LMICs	Studies involving -Pregnant women -Patients with multi-morbidities
Intervention	Studies reporting on the delivery of integrated treatment of TB and HIV in LMICs	-Studies describing treatment of only MDR-TB -Studies describing integrated treatment of drug-sensitive TB and HIV -Studies describing integrated treatment of more than 2 diseases (TB/HIV)
Comparison
Outcome(s)	Studies reporting on MDR-TB outcomes and/or their predictors in the setting of integrated therapy for TB/HIV.	Studies describing outcomes that are unrelated to treatment of MDR-TB in the context of integrated TB/HIV therapy
Study design	Observational studies specifically, cohort studies that use quantitative research methods	1) Interventional studies 2) Observational studies other than cohort, e.g. cross-sectional studies 3) Mini-reviews, conference abstracts, letters to editors, editorials, commentaries. 4) Studies whose full data will not be available even upon requesting from the author 5) Duplicates studies: for studies published with the same or different titles or in more than one journal, the most updated version shall be considered.