Table 1.
Microarray result (the list of gene downregulated by FABP7 deficiency in astrocytes)
| Gene symbol | Fold change | p value | Gene name |
|---|---|---|---|
| Fabp7 | 0.00043 | 1.52E−10 | Fatty acid binding protein 7, brain |
| Scpep1 | 0.13733 | 4.24E−08 | Serine carboxypeptidase 1 |
| Pop4 | 0.13878 | 3.30E−09 | Processing of precursor 4, ribonuclease P/MRP family (S. cerevisiae) |
| Slc2a4 | 0.13990 | 1.36E−08 | Solute carrier family 2 (facilitated glucose transporter), member 4 |
| Wdfy1 | 0.17149 | 8.71E−08 | WD repeat and FYVE domain containing 1 |
| Lpl | 0.19016 | 2.30E−04 | Lipoprotein lipase |
| Plvap | 0.22900 | 1.50E−04 | Plasmalemma vesicle–associated protein |
| Irgm2 | 0.24645 | 1.59E−05 | Immunity-related GTPase family M member 2 |
| Fam154b | 0.25515 | 1.45E−02 | Family with sequence similarity 154, member B |
| Gatad2a | 0.28325 | 1.57E−07 | GATA zinc finger domain containing 2A |
| Coil | 0.30704 | 5.02E−07 | Coilin |
| Agfg2 | 0.31200 | 1.03E−05 | ArfGAP with FG repeats 2 |
| Vmn1r48 | 0.32430 | 1.38E−04 | Vomeronasal 1 receptor 48 |
| Zfp672 | 0.36473 | 1.59E−07 | Zinc finger protein 672 |
| Napa | 0.36635 | 1.14E−05 | N-Ethylmaleimide sensitive fusion protein attachment protein alpha |
| Cd59a | 0.38746 | 5.57E−06 | CD59a antigen |
| Lgals4 | 0.39180 | 1.08E−03 | Lectin, galactose binding, soluble 4 |
| Ndrg4 | 0.39226 | 5.01E−06 | N-Myc downstream regulated gene 4 |
| Zfp503 | 0.40874 | 6.51E−06 | Zinc finger protein 503 |
| Eml2 | 0.41099 | 1.11E−03 | Echinoderm microtubule associated protein like 2 |
| Pisd-ps3 | 0.42044 | 8.65E−05 | Phosphatidylserine decarboxylase, pseudogene 3 |
| S100a3 | 0.42260 | 2.68E−02 | S100 calcium binding protein A3 |
| Mrps12 | 0.42286 | 1.37E−06 | Mitochondrial ribosomal protein S12 |
| Tmem88 | 0.42343 | 3.43E−04 | Transmembrane protein 88 |
| Gadd45gip1 | 0.42344 | 4.92E−07 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| Cdk5rap1 | 0.42795 | 2.56E−03 | CDK5 regulatory subunit associated protein 1 |
| Dcx | 0.43198 | 6.03E−03 | Doublecortin |
| Sp8 | 0.43692 | 5.82E−03 | Trans-acting transcription factor 8 |
| Rgs22 | 0.44513 | 3.04E−02 | Regulator of G protein signaling 22 |
| Hebp2 | 0.44852 | 3.45E−05 | Heme binding protein 2 |
| Gdf15 | 0.45464 | 1.44E−04 | Growth differentiation factor 15 |
| Vtn | 0.45624 | 4.73E−02 | Vitronectin |
| Srl | 0.47381 | 2.13E−02 | Sarcalumenin |
| Dlx1 | 0.47564 | 2.88E−03 | Distal-less homeobox 1 |
Shown are representative genes which were downregulated in FABP7-KO astrocytes