Table 4:

Performance diagnostics of LSM assessing fibrosis stages

Fibrosis Stage	AUROC (95% CI)	Cut-off (kPa)	Sens	Spec	PPV	NPV
0 vs. 1–4	0.82 (0.74, 0.90)	7.4	0.76	0.76	0.76	0.76
0–1 vs. 2–4	0.87 (0.78, 0.96)	10.5	0.81	0.83	0.57	0.94
0–2 vs. 3–4	0.94 (0.88, 0.99)	10.5	0.94	0.83	0.53	0.99
0–3 vs. 4	0.92 (0.79, 1.0)	20.9	0.86	0.95	0.55	0.99
SENSITIVITY FIXED AT 0.90
0 vs. 1–4		6.3	0.90	0.53	0.66	0.84
0–1 vs. 2–4		7.4	0.90	0.60	0.38	0.96
0–2 vs. 3–4		10.5	0.90	0.83	0.53	0.99
0–3 vs. 4		7.5	0.90	0.54	0.14	1.0
SPECIFICITY FIXED AT 0.90
0 vs. 1–4		10.2	0.54	0.90	0.87	0.66
0–1 vs. 2–4		13.5	0.67	0.90	0.67	0.91
0–2 vs. 3–4		13.3	0.82	0.90	0.64	0.96
0–3 vs. 4		16.9 v	0.86	0.90	0.40	0.99