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. 2020 Oct 7;10:16680. doi: 10.1038/s41598-020-73497-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Representative SEM micrographs of untreated B. subtilis CN2 cells (a), showing intact and high electron density morphology, 100 µg/mL (b), 125 µg/mL (c) dosage Cu₂O NPs treated cells indicating cytoplasmic injury with disintegrated outer membrane. P. aeruginosa CB1 untreated cells (d), treated with 100 µg/mL (e) and 125 µg/mL (f) dosage of Cu₂O NPs. Scale bar is 1 µm.