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. 2020 Oct 7;10:16716. doi: 10.1038/s41598-020-73889-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation between extracellular and intracellular metabolome and Candida susceptibility to caspofungin and fluconazole. (A,C,E,G) rPCA models calculated on the spaces constituted by the concentration of the molecules significantly different between susceptible (S) and resistant (R) Candida strains. (B,D,F,H) Box plots summarizing the positions of the samples along PC 1. *P < 0.05.