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. 2020 Oct 7;10:16759. doi: 10.1038/s41598-020-73655-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Monkey groups among 39 cynomolgus monkeys. The monkeys were categorized on the basis of the results of the three TB diagnosis methods (mIGRA, TST, and TB culture) according to time (months, M). For M0, M2, M4, M6, M8, M10 and M12, a number means a record was present for that month. All results are presented as a heat map (please see Table S3 for more details). Positive-mIGRA, positive-TST, suspected-TST and positive-TB culture are scored as 2 (red), while indeterminate-mIGRA, negative-mIGRA, negative-TST and negative-TB culture are scored as 0 (blue). The heat map was created by Rstudio Version 1.3.1073 at https://www.rstudio.com (pheatmap package).