Table 1.
Characteristics of pediatric, and adolescent and young adult (AYA) cancer patients
| Pediatric patientsa (N=2,444) | AYA patientsa (N=13,459) | |||
|---|---|---|---|---|
| N | % | N | % | |
| Female | 1,150 | 47.1 | 7,938 | 59.0 |
| White, non-Hispanic | 1,950 | 79.8 | 11,113 | 82.6 |
| Smoking prior to diagnosis (diagnosed 1996–2015)b | - | - | 1,434 | 10.7 |
| Diagnosis year | ||||
| 1986 to 1995 | 603 | 24.7 | 2,955 | 22.0 |
| 1996 to 2005 | 795 | 32.5 | 4,296 | 31.9 |
| 2006 to 2015 | 1,046 | 42.8 | 6,208 | 46.1 |
| Census tract SES quartilesc | ||||
| Highest SES | 762 | 31.2 | 3,867 | 28.7 |
| High SES | 660 | 27.0 | 3,897 | 29.0 |
| Low SES | 591 | 24.2 | 3,113 | 23.1 |
| Lowest SES | 431 | 17.6 | 2,582 | 19.2 |
| Cancer diagnosis | ||||
| Leukemiasd | 722 | 29.5 | 586 | 4.4 |
| Lymphoid Leukemia | 581 | 23.8 | ||
| Lymphomasd | 256 | 10.5 | 1,420 | 10.6 |
| Hodgkin lymphomas | 84 | 3.4 | 729 | 5.9 |
| Non-Hodgkin lymphomas | 96 | 3.9 | 628 | 4.7 |
| Central nervous system, cranial, and spinal neoplasmsd | 569 | 23.3 | 714 | 5.3 |
| Malignant bone cancersd | 120 | 4.9 | 286 | 2.1 |
| Sarcomas, all sitesd | 356 | 2.7 | ||
| Soft tissue and heart | 160 | 6.6 | 283 | 2.1 |
| Germ cell, trophoblastic, and gonad tumorsd | 93 | 3.8 | 184 | 1.4 |
| Neuroblastoma and peripheral nervous cell tumorse | 177 | 7.2 | - | - |
| Retinoblastomae | 55 | 2.3 | - | - |
| Renal tumorse | 124 | 5.1 | - | - |
| Hepatic tumorse | 48 | 2.0 | - | - |
| Other malignant epithelial neoplasm and melanomase | 108 | 4.4 | - | - |
| Other and unspecified malignant neoplasmse | 12 | 0.5 | - | - |
| Melanoma and skin carcinomasf | - | - | 2,140 | 15.9 |
| Carcinomasf | - | - | ||
| Breast | - | - | 1,365 | 10.1 |
| Cervical | - | - | 714 | 5.3 |
| Colorectal | - | - | 555 | 4.1 |
| Kidney and renal pelvis | - | - | 182 | 1.4 |
| Lung | - | - | 123 | 0.9 |
| Testicular | - | - | 1,323 | 9.8 |
| Thyroid | - | - | 2,292 | 17.0 |
| Other | - | - | 807 | 6.0 |
| Miscellaneous specified neoplasms, NOSf | - | - | ||
| Unspecified Malignant Neoplasmsf | 12 | 0.5 | 16 | 0.1 |
| Stage at diagnosis | ||||
| Distant | 373 | 15.3 | 1,369 | 10.2 |
| Excluding Leukemias | ||||
| Localized | 917 | 37.5 | 7,922 | 58.9 |
| Regional | 381 | 15.6 | 3,241 | 23.9 |
| Unstaged | 51 | 2.1 | 319 | 2.4 |
| Deaths within 10 year | ||||
| All-cause deaths | 428 | 17.5 | 2,156 | 16.0 |
| Cancer-related deaths | 380 | 15.6 | 1,753 | 13.0 |
a
Pediatric patients diagnosed with their first primary cancer 0–14 years; AYA patients diagnosed with their first primary cancer 15–39 years;
b
Denominator is AYA 10,501 patients diagnosed from 1996 to 2015;
c
Computed using the Yost index;
d
Common cancers between the International Classification of Childhood Cancer (ICCC) and AYA ICD-O-3/WHO 200 classification (AYA/WHO) systems;
e
Cancers specific to the ICCC;
f
Cancers specific to the AYA/WHO; Italics indicate values for a subset.